ABSTRACT
Abstract: Ecthyma gangrenosum is a rare skin infection classically associated with Pseudomonas aeruginosa. We performed a retrospective study of all cases diagnosed with ecthyma gangrenosum from 2004-2010 in a university hospital in Mexico (8 cases, 5 female patients and 3 male patients, ages between 4 months and 2 years). The most common risk factor for ecthyma gangrenosum is neutropenia in immunocompromised patients. In previously healthy patients, immunological evaluation is important to rule out underlying immunodeficiency. Ecthyma gangrenosum in healthy patients has a high mortality rate and early diagnosis and aggressive antibiotic treatment is imperative as it can improve patients' prognosis.
Subject(s)
Humans , Male , Female , Infant , Child, Preschool , Pseudomonas aeruginosa/isolation & purification , Pseudomonas Infections/complications , Ecthyma/microbiology , Gangrene/microbiology , Retrospective Studies , Ecthyma/drug therapy , Gangrene/drug therapySubject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Hospitals, University/statistics & numerical data , Influenza A Virus, H1N1 Subtype , Influenza, Human/epidemiology , Asthma/epidemiology , Comorbidity , Mexico/epidemiology , Obesity/epidemiology , Pneumonia/epidemiologyABSTRACT
El penfigoide ampollar es una enfermedad ampollar autoinmune adquirida, que afecta predominantemente a los ancianos y es extremadamente rara en niños. Presentamos el caso de un lactante de 5 meses que ingresa a urgencias por una dermatosis generalizada, caracterizada por ampollas de contenido claro en piel y sin involucrar mucosas. Se corroboró el diagnóstico de penfigoide ampollar por histopatología e inmunofluorescencia directa. El tratamiento consistió en esteroides orales y cuidados de la piel. La paciente ha tenido seguimiento por casi un año y no ha habido recidiva de la enfermedad. El penfigoide ampollar es una enfermedad rara en la infancia, cuya incidencia exacta se desconoce, pero generalmente es de buen pronóstico y su resolución espontánea.
Bullous pemphigoid is an acquired autoimmune disease that mostly affects the elderly and is extremely rare in children. We present the case of a 5 months old infant who was admitted in the emergency department with a generalized dermatosis characterized by skin tense blisters with clear content that spared the mucous membranes. The histopathological and direct immunofluorescence studies confirmed the diagnosis of bullous pemphigoid. The treatment consisted in oral steroids and skin care. The patient has been followed up for almost a year without recurrences. Bullous pemphigoid is a rare disease in childhood with an unknown exact incidence, but with good prognosis and usually self-limited.